BOPI 10 BR/2023 REPERTOIRE NUMERIQUE 11 (11) 21181 (51) A61K 35/761 (2018.01); A61K 39/12 (2018.01); A61K 9/00 (2018.01); A61K 9/16 (2018.01); C12N 1/04 (2018.01); C12N 7/00 (2018.01) (21) 1202100326 - PCT/SE2020/050011 (22) 09/01/2020 (30) SE n° 1950019-8 du 09/01/2019 (54) Stabilized non-enveloped virus compositions. (72) CONRADSON, Göran (SE) et ACEVEDO FONSECA, Fernando (SE) (73) ZICCUM AB, Scheelevägen 22, SE-223 63, LUND (SE) (74) S.C.P AKKUM, AKKUM & Associates, n° 1777, Rue 6.261, Auditorium Jean Paul II, Quartier Mbankolo, B.P. 4966, YAOUNDE (CM). (57) The present invention relates to methods and compositions of thermostable nonenveloped virus as obtained by a laminar counter-current spray drying process. The compositions comprise aerosolizable amorphous particles, comprising free, non-encapsulated nonenveloped virus and an excipient, wherein the particles typically have a mass median aerodynamic diameter (MMAD) of less 5 µm and comprise less than 5% water. Fig. 4 Consulter le mémoire (11) 21182 (51) B01D 33/04 (2018.01); B01D 33/056 (2018.01); B01D 33/66 (2018.01) (21) 1202100365 - PCT/EP2019/053789 (22) 15/02/2019 (54) Filtration apparatus and method. (72) MELHUS, Trond (NO) (73) PRO-FLO AS, Postboks 8034, 4068 STAVANGER (NO) (74) SPOOR & FISHER Inc. NGWAFOR & PARTNERS SARL, The House of Gideon, Golf/Bastos Quarters, Opposite The American Embassy, Entrance-Saint John Paul II Boulevard, B.P. 8211, YAOUNDE (CM). (57) A filtration apparatus (10) for filtrating particles from fluid. the filtration apparatus (10) comprising a filtration vessel (12); -at least one filtering element (14) being arranged to move along a path (20) into the filtration vessel (12); and out from the filtration vessel (12); a filtration inlet (16) arranged to convey a mixture of particles and fluid to the at least one filtering element (14) within the filtration vessel (12), and the filtration outlet (18) arranged to convey fluid, filtrated by the at least one filtering element (14), out from the filtration vessel (12), wherein the filtration apparatus (10) is configured to establish a differential pressure over the at least one filtering element (14) inside the filtration vessel (12). A method of filtrating particles from fluid is also provided.
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