BOPI 02 BR/2023 REPERTOIRE NUMERIQUE 16 Planche Unique Consulter le mémoire ________________________________________ (11) 20789 (51) A61K 38/00 (2018.01); A61K 48/00 (2018.01); A61P 35/00 (2018.01); C12N 15/52 (2018.01); C12N 9/22 (2018.01) (21) 1202100057 - PCT/KR2019/010110 (22) 09/08/2019 (30) KR n° 10-2018-0093336 du 09/08/2018 (54) Novel CRISPR-Associated Protein And Use Thereof. (72) CHOE, Sunghwa (KR); KIM, Han Seong (KP); KIM, Dong Wook (KP); PARK, Jongjin (KP) et YOON, Jiyoung (KP) (73) G+Flas Life Sciences, 1F, 38, Nakseongdae-ro, Gwanak-gu, SEOUL 08790 (KR) et Seoul National University R&DB Foundation, 1, Gwanak-ro, Gwanak-gu, SEOUL 08826 (KR) (74) SPOOR & FISHER Inc. NGWAFOR & PARTNERS Sarl, The House of Gideon, Golf/Bastos Quarters, Opposite The American Embassy, Entrance-Saint John Paul II Boulevard, P.O. Box 8211, YAOUNDE (CM). (57) The present invention relates to a novel CRISPRassociated protein and a use thereof. A protein represented by an amino acid sequence of SEQ ID NO: 1 or SEQ ID NO: 3, according to the present invention, exhibits the activity of endonucleases, which recognize and cleave an intracellular nucleic acid sequence linked to a guide RNA. Therefore, a novel CRISPRassociated protein of the invention can be used as a different nuclease for genome editing, in a CRISPR-Cas system. Fig. 10 Consulter le mémoire ________________________________________ (11) 20790 (51) C10L 1/00 (2018.01); C10L 1/14 (2018.01) (21) 1202100078 (22) 05/02/2021 (54) Biocarburant à base des eaux de rejet issues de la transformation du tubercule de manioc. (72) EDI Abé Valère (CI) (73) EDI Abé Valère, 06 B.P. 427, ABIDJAN 06 (CI) (57) La présente invention décrit un procédé technologique qui permet de produire du bioéthanol inodore et incolore compatible avec les véhicules à essence à partir des eaux de rejet issues de tout type de transformation du tubercule de manioc (Manihot Esculenta Crantz).
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