BOPI 04 BR/2023 REPERTOIRE NUMERIQUE 11 (11) 20881 (51) A61K 31/4439 (2018.01); A61K 31/444 (2018.01); A61K 31/538 (2018.01); A61P 35/00 (2018.01); C07D 401/12 (2018.01); C07D 401/14 (2018.01); C07D 405/14 (2018.01); C07D 413/14 (2018.01) ; C07D 487/04 (2018.01) (21) 1202000048 - PCT/US2017/067516 (22) 20/12/2017 (30) US n° 62/437,384 du 21/12/2016 (54) Pyrazole derivatives as MALT1 inhibitors. (72) WU, Tongfei (BE); LU, Tianbao (US); ALLISON, Brett Douglas (US); BARBAY, Joseph Kent (US); CONNOLLY, Peter J. (US); CUMMINGS, Maxwell David (US); DIELS, Gaston (BE); EDWARDS, James Patrick (US); KREUTTER, Kevin D. (US); PHILIPPAR, Ulrike (BE); SHEN, Fang (US); THURING, Johannes Wilhelmus John Fitzgerald (BE) et BERTHELOT, Didier Jean-Claude (FR) (73) JANSSEN PHARMACEUTICA NV, Turnhoutseweg 30, BEERSE 2340 (BE) (74) S.C.P AKKUM, AKKUM & Associates, n° 1777, Rue 6.261, Auditorium Jean Paul II, Quartier Mbankolo, B.P. 4966, YAOUNDE (CM). (57) Disclosed are compounds, compositions and methods for treating of diseases, syndromes, conditions, and disorders that are affected by the modulation of MALT1. Such compounds are represented by Formula (I) as follows : Formula (I) wherein R1, R2, R3, R4, R5, R6, R5, G1, and G2 are defined herein. Consulter le mémoire ________________________________________ (11) 20882 (51) B01D 29/01 (2018.01); B07B 1/46 (2018.01) (21) 1202000209 - PCT/US2018/040998 (22) 06/07/2018 (30) US n° 15/851099 du 21/12/2017; US n° 62/648771 du 27/03/2018; US n° 15/965195 du 27/04/2018 (54) Injection molded screening apparatuses and methods. (72) WOJCIECHOWSKI Keith (US) (73) Derrick Corporation, 590 Duke Road, BUFFALO, New York 14225 (US) (74) Cabinet ÉKÉMÉ LYSAGHT SARL, B.P. 6370, YAOUNDE (CM). (57) Screening members (16), screening assemblies (10), methods for fabricating screening members and assemblies and methods for screening materials arc provided for vibratory screening machines that incorporate the use of injection molded materials. Use of injection molded screen elements provide, inter alia, for: varying screening surface (11) configurations; fast and relatively simple screen assembly fabrication: and a combination of outstanding screen assembly mechanical and electrical properties, including toughness, wear and chemical resistance. Embodiments of the present invention use a thermoplastic injection molded material.
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