BOPI 04 BR/2023 REPERTOIRE NUMERIQUE 14 Fig. 1 Consulter le mémoire ________________________________________ (11) 20886 (51) A61K 38/03 (2018.01); A61K 39/00 (2018.01); A61K 39/015 (2018.01); A61P 33/06 (2018.01); C07K 16/20 (2018.01) (21) 1202100486 - PCT/EP2020/062167 (22) 30/04/2020 (30) EP n° PCT/EP2019/061135 du 30/04/2019 (54) Antibodies binding to plasmodium circumsporozoite protein and uses thereof. (72) CORTI, Davide (CH); PICCOLI, Luca (CH); FINK, Katja (CH) et CAMERONI, Elisabetta (CH) (73) 1- Humabs BioMed SA, Via dei Gaggini 3, 6500 BELLINZONA (CH) et 2- Vir Biotechnology, Inc., 499 Illinois St, Suite 500, SAN FRANCISCO, California 94158 (US) (74) SPOOR & FISHER Inc. NGWAFOR & PARTNERS Sarl, The House of Gideon, Golf/Bastos Quarters, Opposite The American Embassy, Entrance-Saint John Paul II Boulevard, P.O. Box 8211, YAOUNDE (CM). (57) The present invention provides antibodies targeting Plasmodium sporozoites, in particular Plasmodium circumsporozoite protein. The invention also provides nucleic acids that encode such antibodies. In addition, the invention provides the use of the antibodies of the invention in prophylaxis and treatment malaria. Fig. 5A Fig. 5B Consulter le mémoire
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