BOPI 06 BR/2023 REPERTOIRE NUMERIQUE 25 Consulter le mémoire ________________________________________ (11) 21003 (51) A61K 31/519 (2018.01); A61K 31/5355 (2018.01); A61P 31/18 (2018.01); C07D 239/70 (2018.01); C07D 239/91 (2018.01); C07D 401/12 (2018.01); C07D 471/04 (2018.01) ; C07D 487/02 (2018.01) (21) 1202200284 - PCT/RU2021/000070 (22) 18/02/2021 (30) RU n° No 2020107455 du 19/02/2020 (54) Pyrimidine-based bicycles as antiviral agents for the treatment and prevention of HIV infection. (72) KURKIN, Alexander Vitalievich (RU); MANASOVA, Ekaterina Vladimirovna (RU); KAZYULKIN, Denis Nikolaevich (RU); IVANOV, Vladimir Nikolaevich (RU) et SHURYGIN, Mikhail Gennadievich (RU) (73) PHARMASYNTEZ, JOINT STOCK COMPANY, Krasnogvardeyskaya street, 23, office 3, IRKUTSK 664007 (RU) (74) SCP ATANGA IP, 2nd Floor Floor Tayou Bldg, Fokou Douche Akwa, P.O. Box 4663, DOUALA (CM). (57) This invention relates to pyrimidine derivatives, having HIV replication inhibiting. The present invention provides new pyrimidine compounds, designed for the treatment and prevention of HIVmediated diseases. The invention further relates to pharmaceutical compositions and drugs contained in them. The invention also relates to the use of abovementioned compounds for the treatment and/or prevention of HIV in subjects with HIV-infection (human immunodeficiency virus) or having risk of getting HIV-infection. Formula I Consulter le mémoire ________________________________________ (11) 21004 (51) A61K 36/00 (2018.01); A61K 36/324 (2018.01) ; A61P 31/00 (2018.01) (21) 1202200303 (22) 23/06/2022 (54) Extrait de Boswellia dalzielii pour l’efficacité des antibiotiques de la famille des β-lactamines. (72) TIEMTORE Rahimatou Yasmine Wendkuni (BF); METUOR DABIRE Amana (BF); OUERMI Djénéba (BF); DJIGMA Florencia Wendkuuni (BF); ZONGO Luc (BF) et SIMPORE Jacques (BF) (73) Université Joseph KI-ZERBO (UJKZ), 03 B.P. 7021, OUAGADOUGOU 03 (BF) (57) L’invention concerne des extraits à base de Boswellia dalzielii utilisée en association avec les
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