BOPI 09 BR/2023 REPERTOIRE NUMERIQUE 15 (30) US n° 62/916,680 du 17/10/2019; US n° 62/925,672 du 24/10/2019 (54) Fabrication of carbon fibers with high mechanical properties. (72) CHEN, Weixing (CA) (73) Tangold Inc., 9407-3 20th Avenue NW, EDMONTON, Alberta T6N 1E5 (CA) (74) SPOOR & FISHER Inc. NGWAFOR & PARTNERS SARL, The House of Gideon, Golf/Bastos Quarter, Opposite The American Embassy, Entrance-Saint John Paul II Boulevard, B.P. 8211, YAOUNDE (CM). (57) A method of fabricating carbon fibers includes the steps of : (a) melting aspirartene solids in a scaled vessel ; (b) spimiing melted asplialtenes to fabricate green fibers ; (c) stabilizing the green fibers ; (d) carbonizing the stabilized green fibers; and (e) optionally graphilizing carbonized fibers. Consulter le mémoire ________________________________________ (11) 21139 (51) A61K 31/4375 (2018.01); C07D 207/04 (2018.01) ; C07D 471/04 (2018.01) (21) 1202200154 - PCT/US2020/055986 (22) 16/10/2020 (30) US n° 62/916,062 du 16/10/2019 (54) Inhibiting human integrin ALPHA4BETA7. (72) ROGERS, Bruce N. (US); BURSAVICH, Matthew G. (US); CUI, Dan (US); DOWLING, James E. (US); HAHN, Kristopher N. (US); HARRISON, Bryce A. (US); LIN, Fu-Yang (US); LIPPA, Blaise S. (US); TROAST, Dawn M. (US); ZHONG, Cheng (US); KONZE, KyleD. (US); GERASYUTO, Aleksey I. (US); KIM, Byungchan (US); RAFI, Salma (US); DAY, Tyler (US); HICKEY, Eugene (US); HOUANG, Evelyne (US) et ZAHLER, Robert (US) (73) Morphic Therapeutic, Inc., 35 Gatehouse Drive, A2 WALTHAM, MA 02451 (US) (74) SPOOR & FISHER Inc. NGWAFOR & PARTNERS SARL, The House of Gideon, Golf/Bastos Quarter, Opposite The American Embassy, Entrance-Saint John Paul II Boulevard, B.P. 8211, YAOUNDE (CM). (57) Disclosed are small molecule antagonists of human α4β7 integrin, and methods of using them to treat a number of diseases and conditions. Formula I
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