BOPI 03 BR/2024 REPERTOIRE NUMERIQUE 12 (11) 21433 Consulter le mémoire (51) A61K 35/66 (2018.01); A61K 36/185 (2018.01) ; A61K 45/06 (2018.01) (21) 1202100558 - PCT/US2020/036356 (22) 05/06/2020 (30) US n° 62/858,571 du 07/06/2019 (54) Cacao cell suspension protocol. (72) MARELLI, Jean-Philippe (US); GARCIA, Claudia Yanet (US); BRITTO, Dahyana (US) et SILVA, Lidiane Dos Santos (US) (73) MARS, INCORPORATED, 6885 Elm Street, MCLEAN, Virginia 22101-3883 (US) (74) SPOOR & FISHER Inc. NGWAFOR & PARTNERS Sarl, The House of Gideon, Golf/Bastos Quarters, Opposite The American Embassy, Entrance-Saint John Paul II Boulevard, P.O. Box 8211, YAOUNDE (CM). (57) Provided herein are methods for establishing Theobroma cell suspension cultures using young leaves as a source of explants. Also provided are induction, proliferation, and suspension media used for producing Theobroma cell suspension cultures. These methods and media may be useful for producing secondary metabolites in Theobroma, as well as for isolating virus particles associated with Theobroma diseases. Fig. 5 ________________________________________ (11) 21434 Consulter le mémoire (51) A61K 31/444 (2018.01); A61P 35/00 (2018.01); C07D 401/14 (2018.01) (21) 1202200245 - PCT/US2020/066021 (22) 18/12/2020 (30) US n° 62/950,815 du 19/12/2019; US n° 63/032,473 du 29/05/2020; US n° 63/089,497 du 08/10/2020 (54) Compounds and methods for the targeted degradation of androgen receptor. (72) CREW, Andrew P. (US); DONG, Hanqing (US); SNYDER, Lawrence B. (US) et WANG, Jing (US) (73) ARVINAS OPERATIONS, INC., 5 Science Park, 395 Winchester Avenue, NEW HAVEN, Connecticut 06511 (US)
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