BOPI 04 BR/2024 REPERTOIRE NUMERIQUE 19 and pharmaceutical compositions thereof. Also disclosed herein are methods of making the phannaceutical compositions of the 19-nor C3,3disubstituted C21-pyrazolyl steroid of formula (I) and methods of using the 19-nor C3,3disubstituted C21-pyrazolyl steroid of formula (I) or crystalline solid forms, pharmaceutically acceptable salts, and pharmaceutically acceptable compositions thereof. Formula I & Fig. 7 ________________________________________ (11) 21492 Consulter le mémoire (51) A61M 16/00 (2018.01); A61M 16/06 (2018.01); A61M 16/20 (2018.01) ; A62B 7/04 (2018.01) (21) 1202300033 - PCT/US2021/043333 (22) 27/07/2021 (30) US n° 63/056, 944 du 27/07/2020; US n° 17/068, 718 du 12/10/2020 (54) Automatic system for the conservation of oxygen and other substances. (72) BAZOBERRY, Carlos, Fernando (US) et YOUNG, Brent, H. (US) (73) OXFO CORPORATION, 110 Fairway Road, CHESTNUT HILL, MA 02467 (US) (74) Cabinet Spoor & Fisher Inc. Ngwafor & Partners, The House of Gideon, Golf/Bastos Quater, Opposite The American Embassy, Entrance-Saint John Paul II Boulevard, P.O. Box 8211, YAOUNDE (CM). (57) A system (10) and method for conserving oxygen and other gases supplied to a recipient. A supply conduit (408) supplies gas from a source (406) to a reservoir (404), which retains a volume of gas at ambient pressure. A conduit (422) supplies gas from the reservoir (404) to the recipient. An inflation detection system, such as an electromechanical system or a contactless system (456), detects when the reservoir (404) is below a state of inflation and when the reservoir (404) is inflated to the state of inflation. A valve system prevents gas from flowing from the source (406) and into the reservoir (404) when the reservoir (404) is at the predetermined state of inflation, and the valve system permits gas to flow from the source (406) into the reservoir (404) when the reservoir (404) is below the predetermined state of inflation whereby gas within the reservoir (404) can be continually replenished without pressurization above ambient pressure.
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